More than 130 practices in over 115 locations

Palmetto Health-USC Medical Group is the largest multispecialty, clinically integrated medical group providing the broadest range of health care services in the Midlands region.

The Most Advanced Care in the Region


Recent News

Prisma Health welcomes 15 cardiologists from Columbia Heart

Cardiology practice joins Palmetto Health-USC Medical Group.

Featured Physician

Show your heart some love

February is American Heart Month, and Prisma Health is offering a series of free seminars led by cardiology providers.

Health Risk Assessment

What’s your heart age?

Take a fast, free heart health assessment.

More than 800 providers

Along with our 2,400 team members, we offer patients the broadest range of health care services in the Midlands.

Get the Facts

Our affiliate system

Prisma Health is the largest not-for-profit health organization in South Carolina, serving more than 1.2 million patients annually. Our 30,000 team members are dedicated to supporting the health and well-being of you and your family. Palmetto Health-USC Medical Group will be rebranded at a later date and will continue to operate as a joint venture between the Midlands affiliate and the USC School of Medicine.

Our promise is to: Inspire health. Serve with compassion. Be the difference.

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Palmetto Health is now Prisma Health. Palmetto Health-USC Medical Group is part of Prisma Health.